diff --git a/test/Transforms/InstCombine/call-intrinsics.ll b/test/Transforms/InstCombine/call-intrinsics.ll
new file mode 100644
index 00000000000..07435c4a3bd
--- /dev/null
+++ b/test/Transforms/InstCombine/call-intrinsics.ll
@@ -0,0 +1,17 @@
+; RUN: llvm-as < %s | opt -instcombine | llvm-dis
+
+declare void %llvm.memmove(sbyte*, sbyte*, uint, uint)
+declare void %llvm.memcpy(sbyte*, sbyte*, uint, uint)
+declare void %llvm.memset(sbyte*, ubyte, uint, uint)
+
+%X = global sbyte 0
+%Y = global sbyte 12
+
+void %zero_byte_test() {
+  ; These process zero bytes, so they are a noop.
+  call void %llvm.memmove(sbyte* %X, sbyte* %Y, uint 0, uint 100)
+  call void %llvm.memcpy(sbyte* %X, sbyte* %Y, uint 0, uint 100)
+  call void %llvm.memset(sbyte* %X, ubyte 123, uint 0, uint 100)
+  ret void
+}
+