diff --git a/test/Transforms/InstCombine/and-compare.ll b/test/Transforms/InstCombine/and-compare.ll
new file mode 100644
index 00000000000..35516a5065b
--- /dev/null
+++ b/test/Transforms/InstCombine/and-compare.ll
@@ -0,0 +1,10 @@
+; RUN: llvm-as < %s | opt -instcombine | llvm-dis | grep and | wc -l | grep 1
+
+; Should be optimized to one and.
+bool %test1(uint %a, uint %b) {
+        %tmp1 = and uint %a, 65280
+        %tmp3 = and uint %b, 65280
+        %tmp = setne uint %tmp1, %tmp3
+        ret bool %tmp
+}
+